ANDARINE S4 Capsules

S-4 Andarine Capsules Bulgaria

S-4, commonly known as Andarine, is a Selective Androgen Receptor Modulator (SARM). It has attracted attention for its potential benefits in skeletal muscle growth and performance enhancement. S-4, classified as a SARM, binds selectively to androgen receptors, particularly in muscle and bone tissues. This selective binding is part of its action and is believed to help increase lean muscle mass, strength, and performance. It may do so without the adverse effects often linked to traditional anabolic steroids.

One of the primary advantages of S-4 Andarine capsules is its potential to increase muscle mass through strong androgen binding. This may lead to greater muscle tissue size and anabolic activity. S-4 has also been suggested to improve endurance and stamina, allowing individuals to push through intense workouts with more energy and resilience.

Despite its potential benefits, it’s essential to use caution. Researchers discontinued the early clinical development of S-4, and they never advanced the compound to approved medical use. It is not approved for human use and is limited to clinical research. Like other SARMs, S-4 may affect testosterone production and estrogen levels, which can lead to hormone changes such as testosterone suppression.

Bulgaria Benefits of S-4 Andarine Capsules

Bone & Muscle Wasting

This selective androgen receptor modulator may help reduce muscle loss and preserve gains from anabolic cycles. Bulgaria Research has suggested S-4 Andarine was first developed to treat osteoporosis. This disease weakens bone mineral density and makes bones brittle. It was studied because of its ability to improve total body bone strength.

Other uses have included research on muscle wasting diseases, benign prostatic hyperplasia (BPH), and even early studies on prostate cancer (not an approved treatment). In preclinical work with male rats, researchers measured levator ani muscle size and levator ani muscle weight to evaluate androgenic activity.

Increased Muscle Mass

In laboratory research, S-4 Andarine Capsules showed promise for improving bone, muscle density, and strength without causing water retention. It works by binding to androgen receptors in bone and muscle. This changes gene expression and boosts muscle protein synthesis and body anabolism. Increased vascularity, muscle hardness, and lean, strong muscle may appear during an S4 Andarine cycle.

Cut & Bulk

Because of its high oral bioavailability, Andarine S4 capsules are considered flexible. It may be used to cut, recompose, or bulk. For optimal results in experimental settings, controlled dosage adjustments are key. Community reports and comparative studies sometimes mention Cardarine, though these are anecdotal and not based on clinical practice.

Anabolic Effects

While S-4 Andarine capsules are less anabolic than other SARMs, they are still highly androgenic. S-4 is often called the least anabolic but most androgenic SARM on the market. Its androgenic activity and androgenic effects may help promote fat oxidation when binding to receptors. Animal studies found that it reduced stubborn abdominal and visceral fat. Research subjects often report outcomes such as fat loss, muscle gain, better physique, and higher energy. Secondary effects such as changes in growth hormone and possible endocrine disruption are still under study.

Fat Loss

Studies on animal models also indicate that the S4 Andarine compound adds resilience and power, even in a caloric deficit. In addition to weight and fat loss, S-4 Andarine Capsules may also help support the gain of lean mass.

Is Andarine (S-4) Safe?

The safety of S-4 Andarine capsules remains debated in the current opinion of the scientific community. It acts as a partial agonist and is sometimes described as a partial agonist of the androgen receptor. This is different from a full agonist, which may carry stronger risks.

Reported side effects and potential side effects include issues with ocular receptors that may cause night blindness or a yellow tint in vision. These vision-related effects were a key reason the development of S-4 was halted. They are dose-dependent and usually reversible when discontinued, based on research reports and observations.

Other concerns include possible liver strain (not well studied in humans). Hormone-related changes such as testosterone suppression and estrogen imbalance have also been seen in research settings.

Longer cycle length may increase the chance of serious adverse events. No completed human clinical trials confirm long-term safety. The pharmacodynamics of selective androgen receptor modulators are still under study. References in the Journal of Medicinal Chemistry highlight both risks and potential uses. Because of missing data and unclear legal status in the United States, the compound is limited to laboratory use.

Some Bulgaria researchers suggest PCT (post-cycle therapy) may help restore natural testosterone production after studies. Until stronger evidence is available, S-4 should only be considered for clinical research, with guidance from qualified healthcare professionals.

Like our S-4 Andarine Capsules? Shop more Andarine S-4 Liquid products here from Direct SARMS Bulgaria

References:

[1] Gao W, Reiser PJ, Coss CC, Phelps MA, et al. Selective androgen receptor modulator treatment improves muscle strength and body composition and prevents bone loss in orchidectomized rats. Endocrinology. 2005 Nov;146(11):4887-97.

[2] Girgis CM, Mokbel N, Digirolamo DJ. Therapies for musculoskeletal disease: can we treat two birds with one stone? Curr Osteoporos Rep. 2014 Jun;12(2):142-53.

[3] Yavuz M, Demircan T. Exploring the potentials of S4, a selective androgen receptor modulator, in glioblastoma multiforme therapy. Toxicol Appl Pharmacol. 2024 Sep;490:117029.

[4] Bhasin S, Jasuja R. Selective androgen receptor modulators as function promoting therapies. Curr Opin Clin Nutr Metab Care. 2009 May;12(3):232-40.

Formula: C19H18F3N3O6

Molar mass: 441.357 g/mol

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DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Bulgaria Direct Sarms website is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.